BioMatrix Licorice Root Extract supports the adrenal glands when cortisol levels are low. A primary compound in licorice root is glycyrrhizin (a substance that has a molecular structure similar to corticosteroids). As such, licorice root aids in adrenal function by partially blocking the enzyme that converts cortisol to cortisone, thus sparing cortisol.* BioMatrix licorice root is 100% organic.